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Normally there has to be a medical reason for this, like being allergic to one of the in-active ingredients in fosamax or something else along those lines.

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answer fosamax will not lose it s effectiveness but it is very hard to absorb.

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dear dr lynch,perhaps you should also be clnilag insanely irresponsible the 2010 aaos meeting which presented studies from the hospital for special surgery hss and columbia university medical center which showed that fosamax disturbs bone formation, and implicated fosamax in spontaneous mid-femur fractures without trauma .

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always take fosamax exactly as it was prescribed to you by your doctor.
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Always take fosamax first thing in the morning 30 minutes before you eat or drink anything or take any other medications.

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