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As will be discussed below, by accumulating in the acidic organelles, chloroquine exerts both direct antiviral effects on enveloped viruses and decreases activation of several cell types involved in the immune response.

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chloroquine is a chemotherapeutic agent for the clinical treatment of malaria.

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mefloquine is used to help prevent developing malaria in areas of the world where there is a high risk of chloroquine-resistant falciparum malaria.

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