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Zyloprim allopurinol is metabolized to the corresponding xanthine analogue, oxipurinol alloxanthine , which also is an inhibitor of xanthine oxidase.

Another treatment is supportive care in which the symptoms of allopurinol overdose are treated.

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It has also been shown that people taking an antibiotic called amoxicillin at the same time as allopurinol are more likely to develop a rash, possibly due to an interaction between the drugs.

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