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sinemet cr and half sinemet cr are a combination of carbidopa, an aromatic amino acid decarboxylase inhibitor, and levodopa, the metabolic precursor of dopamine, in a polymer-based controlled-release tablet formulation, for use in the treatment of parkinson s disease.
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sinemet may be given to patients with parkinson s disease and syndrome who are taking vitamin preparations that contain pyridoxine hydrochloride vitamin b6 .
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although the effects of sinemet on human pregnancy are unknown, both levodopa and combinations of carbidopa and levodopa have caused visceral and skeletal malformations in rabbits.
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